2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
Jedi2
CAS: 651005-90-2
Molecular Formula: C10H8O3S
2-Methyl-5-(2-thienyl)-3-furancarboxylic acid - Names and Identifiers
| Name | Jedi2 |
| Synonyms | Jedi2 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid |
| CAS | 651005-90-2 |
2-Methyl-5-(2-thienyl)-3-furancarboxylic acid - Physico-chemical Properties
| Molecular Formula | C10H8O3S |
| Molar Mass | 208.23 |
| Appearance | Solid |
| Storage Condition | 2-8°C，密封，干燥 |
| MDL | MFCD01569561 |
| In vitro study | Jedi2 evokes Piezo1-mediated Ca 2+ influx. Jedi2 (200 μM) specifically elicits dose-dependent responses in mPiezo1-transfected cells, but not in mPiezo2- or vector-transfected cells . Jedi2 (1 mM) causes an increase in Ca 2+ in mCherry-positive HEK293T cells transfected with the mPiezo1-mCherry construct, which also responded to Yoda1 (30 μM) . |
2-Methyl-5-(2-thienyl)-3-furancarboxylic acid - Reference Information
| biological activity | Jedi2 is an activator of Piezo1, but not of piezo2. Jedi2 binds to the mouse piez01 protein with a Kd value of 2770 μm. |
Last Update：2024-04-09 20:52:54
